Premular (AUSTL76828) contains a clinically trialled extract (Ze 440) of the herb Vitex agnus-castus, also known as Chaste tree. Each tablet of Premular contains extract equivalent to dry Vitex agnus-castus fruit 180mg. Vitex agnus-castus has a long history of traditional use for hormonal conditions and menstrual complaints. Learn more about Vitex agnus-castus.

Recommended Dosage and Directions

Adults: 1 tablet per day

For best results take Premular for a minimum of 3 months. 

Premular contains a specific extract of the Vitex agnus-castus (Chaste tree), the one that has been used in a number of clinical trials. This extract, referred to as Ze 440, is exclusive to Premular, which means Premular is a Vitex agnus-castus product that has demonstrated significant efficacy in clinical trials, including a double-blind placebo controlled study published in the British Medical Journal.2

One recent publication confirmed that the dose used in Premular is the optimal dose for the relief of PMS symptoms.3

Relief of symptoms: Three published Premular clinical trials suggest significant relief in PMS symptoms for women taking Premular over a 3-month period, and lasting for 3 cycles even after therapy has ceased.2,3

Premular tablets are easy to take and are well tolerated, with millions of doses recommended worldwide. Premular is manufactured in Switzerland according to proven production methods to help ensure you get a consistently reliable medicine, which is the same medicine used in clinical trials. Premular has also been assigned a ‘well established medicinal use status’ a status based on its history, evidence and excellent tolerability.5,6

Premular has no added gluten, wheat soy, sugar, yeast, salt, artificial colours or preservatives.

1. Lentz GM, et al (eds). Comprehensive Gynecolgy 6th Ed 2012. Elsevier Mosby. Chap 36 pp 797-803 2. Schellenberg R et al. BMJ 2001;322:134-137 3. Schellenberg R, et al. Phytomedicine. 2012; pii: S0944-7113(12)00280-2 4. Berger D et al Arch Gynecol Obstet 2000;264:150-153  5. Committee on Herbal Medicinal Products (HMPC). EMEA/HMPC/144003/2009 6. Committee on Herbal Medicinal Products (HMPC). EMA/HMPC/144006/2009 7. Dickerson LM, et al. Am Fam Phys. 2003;67:1743-52 

Some of this research was conducted using funding provided by Max Zeller Soehne AG, the manufacturer of this product.